20 results
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... Decreased Na, K-ATPase ... happypillsrx/ #Hyperkalemia ... Pathophysiology #Pharmacology ... #Renal
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... diagnosis #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• NSAIDs • ACE ... • Recent IV potassium ... Beta blockers • Antibiotics ... diagnosis #causes #potassium ... #high #nephrology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... Increased EC shift of K ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology ... #potassium #medications
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
measuring urinary K ... loss • Renal ... Renal tubular acidosis ... algorithm #causes #nephrology ... #potassium
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Losses Non-renal ... vomiting) • Low K ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... treated with IV potassium ... suggests extra-renal ... #differential #potassium ... #nephrology #low
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... syndrome #hypokalemia ... #urine #potassium ... algorithm #diagnosis #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
NSAIDs, β-blockers, Antibiotics ... - Renal Failure ... Ca-gluconate or 1g CaCl ... Management #Treatment #potassium ... #nephrology #K
Hypokalemia Diagnostic Algorithm
To assess potassium excretion: perform 24-hour urine collection or alternatively obtain potassium-to-creatinine ratio on
Hypokalemia Diagnostic ... (K⁺ <3.5 mEq/L) ... values suggest renal ... K wasting. ... Algorithm #TTKG #nephrology