77 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... of action on the ... Thiazides-type diuretics ... #pharmacology # ... nephrology #medications
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... as no effect on ... #Pharmacology # ... nephrology #conversion
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
acid, Liddle's Syndrome ... >20 mEq/24 h - Diuretics ... , Bartter's syndrome ... , Gitelman's syndrome ... Diagnosis #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
intake, Diuretics ... -: Diuretics, Bartter ... Syndrome, Gitelman ... Syndrome Volume ... Diagnosis #Algorithm #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... Inhibitors of Na+K+2Cl ... and nephrotic syndrome ... and nephrotic syndrome ... #Nephrology #Pharmacology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
intake, Diuretics ... -: Diuretics, Bartter ... Syndrome, Gitelman ... Syndrome Volume ... Diagnosis #Algorithm #Nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
in cardiorenal syndrome ... activities • Diuretic ... release • ↓ Cl ... #cardiorenal #syndrome ... pathophysiology #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
with hypokalemia on ... • Low Urine Cl ... - Loop diuretics ... , Thiazide diuretics ... algorithm #diagnosis #nephrology
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
syndrome) - Osteoblastic ... syndrome) Extrarenal ... Saline or osmotic diuresis ... Drugs: - Loop diuretics ... medications #drugs #pharmacology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
loop or thiazide diuretics ... pressure: Active diuretic ... use, Bartter syndrome ... , Gitelman syndrome ... urine #Algorithm #nephrology