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diagnosis differential hematology arthritis pain disease signs symptoms approach classification erythematosus lupus management sle systemic workup agglutinin algorithm anemia arterial
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Vascular Joint Pain ... Hyperemia Spasm • Vasculitis ... Air Embolism • Vasculitis ... Marfan's Syndrome ... #JointPain #MSK
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Abnormal pathergy test ... , medium-large joints ... ) • Vascular lesions ... and peripheral vascular ... Diagnosis #criteria #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... Non-bloody: OA, avascular ... - parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Etiology: • Vascular ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... /HSP • Cryoglobulinemia ... #rheumatology #
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
present both at rest ... improves quickly with rest ... e.g., congenital hip ... osteopetrosis, avascular ... #Pain #MSK #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... phenomenon (20%) Joints ... Aseptic necrosis of hip ... Demyelinating syndromes ... symptoms #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
and bullous or vesicular ... eruption - Joints ... retinopathy Lab Tests ... Cryoglobulins • HIV ... differential #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Lyme disease, Vasculitis ... Heberden's nodes (DIP ... nodes (PIP joints ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Vascular Sludging ... Hyperviscosity Syndrome ... HBV infection, HIV ... 20% Sjögren's syndrome ... classification #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... and diplopia) • Vascular ... Positive pathergy test ... is a skin prick test ... signs #symptoms #rheumatology
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