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diagnosis differential nephrology causes management classification potassium rhabdomyolysis cancer diuretics excretion hematology hepatology hepatorenal hrs hypokalemia hypophosphatemia leukostasis lysis medications
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... Cancer Related • Hypercalcemia ... malignancies Treatment ... #Kidney #Injury ... #AKI #Cancer #Oncology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Distributive Shock, HRS, Hypercalcemia ... Abdominal Compartment Syndrome ... #Acute #Kidney ... nephrology #causes #algorithm
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
declines > ALT) • AKI ... + myoglobin AKI ... Shift of extracellular ... nephrotoxicity to kidney ... Loop diuretics for
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
, Compartment syndrome ... Dermatomyositis) AKI ... Shift of extracellular ... Loop diuretics for ... Dialysis for severe hyperkalemia
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
Algorithm for patients ... with hypokalemia ... creatinine) • Cell shift ... ↑ Aldosterone: Kidney ... #hypokalemia
Hypophosphatemia - Differential Diagnosis Algorithm Appropriately Low Kidney Phosphate Excretion: • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Appropriately Low Kidney ... Transcellular Shift ... , Acute Respiratory ... Inappropriately High ... Hyperparathyroidism, TKI
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
; High-Ceiling Diuretics ... Torsemide) • Acute ... Hyponatremia • Hypercalcemia ... hyperaldosteronism • Acute ... Tolvaptan) • Treatment
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... IV Fluids • If high ... preload → Diuretics ... #Acute #Kidney ... #Injury #treatment
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... • Triggers: Diuretics ... fever - ACS, AKI ... , acute limb ischemia ... hydration - Hyperkalemia
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
extracellular shift ... Acute oliguric kidney ... injury F. ... antiphospholipid syndrome ... Differential #Diagnosis #High
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