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diagnosis management differential nephrology causes algorithm potassium hypokalemia high pathophysiology tls oncology classification medications tumor cancer gitelman hypermagnesemia hyperphosphatemia hypomagnesemia
Hypokalemia - Differential Diagnosis Algorithm Transcellular Shift: • Alkalosis • ↑ beta-2 adrenergic simulation • Erythropoiesis
Hypokalemia - Differential ... Transcellular Shift ... • Refeeding syndrome ... Transcellular shifts ... MatthewHoMD #Hypokalemia
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Intracellular Shift ... release due to cell lysis ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis
Emergency Management of Hyperkalemia in Adults Assess Patient - Airway Breathing Circulation Disability Exposure (ABCDE) Approach •
Management of Hyperkalemia ... - 6.4 mmol/L - Treatment ... Gluconate IV Shift ... Consider cause of hyperkalaemia ... recurrence #Hyperkalemia
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology of Tumor Lysis ... Syndrome (TLS) ... Tumor Cell Lysis ... Hypocalcemia • Hyperkalemia ... #TumorLysis #Syndrome
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... 6L/day) • For hyperkalemia ... wandering_er #Tumor #Lysis ... #Syndrome #TLS
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Syndrome Leukostasis ... organ damage • Treatment ... Low calcium • Treatment ... hydration - Hyperkalemia ... treatment (no calcium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Intracellular Shift ... release due to cell lysis ... reaction - Tumor lysis ... syndrome - Rhabdomyolysis
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... and Treatment of ... hydroxide • Hyperkalemia ... #TumorLysis #Syndrome
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Intercellular Shift ... Transcellular Shift ... Tumor Lysis Syndrome ... • Digoxin #Hyperkalemia
Hypokalemia Differential Diagnosis Algorithm Low intake • poor oral intake Renal loss • Medication • Hypomagnesemia •
Hypokalemia Differential ... • Gitelman's syndrome ... • Bartter's syndrome ... Transcellular shift ... amzn.to/2LmUODZ #Hypokalemia
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