12 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Agents to Treat Hyperkalemia ... to moderate); hypokalemia ... Hypomagnesemia; hypokalemia ... disturbances (including hypokalemia ... #Hyperkalemia #
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
New Potassium-Binding ... #Potassium #Binding ... KBinders #Kayexelate #Comparison ... #Table #Pharmacology ... #Patiromer #HyperKalemia
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... pathophysiology #pharmacology
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
Plasma-Lyte - Causes hyperkalemia ... patients with hyperkalemia ... #Crystalloids #pharmacology ... #indications #comparison
Intern Pocket Cards - Inpatient Blood Pressure Management Guide
ß-blockers:
 • Metoprolol, Carvedilol, Labetalol
 • Bradycardia, heart
Valsartan • AKI, hyperkalemia ... Spironolactone • AKI, hypovolemia ... medications #Inpatient #pharmacology ... agents #internship #comparison
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Management of Hyperkalemia ... Binders #Management #Hyperkalemia ... #treatment #pharmacology ... #table #comparison
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... works by directly binding ... - Hyperkalemia ( ... , in states of hypokalemia ... CaitEKulig #Digoxin #Pharmacology
Characteristics of Commonly Used Phosphate Binders 
Aluminum 
 - Potent and effective 
 - Useful for
Inexpensive - Treats hypocalcemia ... Lower risk of hypercalcemia ... range - Lack of hypercalcemia ... Binders #Table #Comparison ... #Pharmacology #
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison

Composition of LR:
 • Sodium 130 mEq/L
 •
Saline (NS) - Comparison ... Is Dangerous in Hyperkalemia ... transcellular shift ... Normal #Saline #NS #comparison ... #pharmacology #
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
this pathway, ending ... avoid harmful hyperkalemia ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology