852 results
Pivot-Shift Test in ACL-deficient Knee

This patient has pathologic varus alignment across the knee and a chronic
Pivot-Shift Test ... dr.dold.md #Pivot #Shift ... #PivotShift #test
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Curve Left Shift ... Temperature Right Shift ... Dissociation #Curve #pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Curve Left Shift ... Hypophosphatæmia Right Shift ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift
Normal (Negative) Pivot-Shift Test for ACL Knee Injury

Andrew Dold, MD @dr.dold.md

#Pivot #Shift #PivotShift #test #ACL #Knee
Negative) Pivot-Shift ... dr.dold.md #Pivot #Shift ... #PivotShift #test
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... Transcellular shifts
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Transcellular Shift ... potassium #low #pathophysiology
Conceptual Relationship between Volume Responsiveness and Volume Tolerance

Assessing for volume responsiveness would only tell you that
Causes of "Left Shift ... Tolerance #IVFluids #Shift ... #Differential #Pathophysiology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... differential #diagnosis #pathophysiology
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... driven by insulin) shifts ... details of the pathophysiology ... #Pathophysiology
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Transcellular Shift