26 results
Causes of Hyperkalemia

Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts. The
Causes of Hyperkalemia ... Hyperkalemia is caused ... by excess potassium ... intake, impaired potassium ... transcellular shifts
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Diagnosis #Algorithm #causes ... #potassium #low ... #pathophysiology
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Causes of Hyperkalemia ... Excretion (IV potassium ... Transcellular Shift ... Diagnosis #Algorithm #Causes
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Curve Left Shift ... Hypophosphatæmia Right Shift ... Dissociation #Curve #Pathophysiology ... #Left #Right #Shift ... #Differential #Causes
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Conceptual Relationship between Volume Responsiveness and Volume Tolerance

Assessing for volume responsiveness would only tell you that
Causes of "Left ... Shift" (Decreased ... Tolerance #IVFluids #Shift ... #Differential #Pathophysiology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pharmacology and Pathophysiology ... intracellular calcium causes ... the cell, serum potassium ... the same site as potassium ... #Pharmacology #Pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Diagnosis #Algorithm #causes ... #potassium #high ... #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Dermatomyositis) AKI - Pathophysiology ... Shift of extracellular ... Monitor potassium ... Management #Summary #causes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... Intracellular Shift ... differential #diagnosis #causes ... #potassium #high