42 results
Pivot-Shift Test in ACL-deficient Knee

This patient has pathologic varus alignment across the knee and a chronic
Pivot-Shift Test ... in ACL-deficient ... be performing a high-tibial ... dr.dold.md #Pivot #Shift ... #PivotShift #test
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Angiotensin-converting enzyme (ACE ... • Increased EC shift ... • Exogenous (KCL ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Normal (Negative) Pivot-Shift Test for ACL Knee Injury

Andrew Dold, MD @dr.dold.md

#Pivot #Shift #PivotShift #test #ACL #Knee
Negative) Pivot-Shift ... Test for ACL Knee ... dr.dold.md #Pivot #Shift ... #PivotShift #test ... #ACL #Knee #Injury
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Curve Left Shift ... Temperature Right Shift ... ↑ 2,3-BPG • High ... Dissociation #Curve #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Transcellular Shift ... Algorithm #causes #potassium ... #low #pathophysiology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypertensive: • High ... Al, Low R - Primary ... aldosteronism • High ... Al, High R - Secondary ... #causes #low #potassium
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... mmol creatinine) High ... Urine Cl - Loop ... hypokalemia #urine #potassium
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Aldosterone Release: ACE ... #Hyperkalemia #Pathophysiology ... Pharmacology #Impaired #Potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • NSAIDs • ACE ... • Recent IV potassium ... Intracellular Shift ... #high #nephrology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Dialysis Serum potassium ... blocks, QRS axis shift ... #hyperkalemia #potassium ... #high #diagnosis