19 results
diagnosis differential causes algorithm management treatment nephrology pharmacology hypokalemia cardiology classification comparison curve dissociation druginduced edema effects heat heatstroke hemoglobin
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
and Pathophysiology ... - Hyperkalemia ( ... high potassium levels ... , in states of hypokalemia ... #Pharmacology #Pathophysiology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... : • Digoxin ... • Recent IV potassium ... Intracellular Shift ... #high #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift ... Refeeding Syndrome #Hypokalemia ... Algorithm #causes #potassium ... #low #pathophysiology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Increased EC shift ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... : • Digoxin ... • Recent IV potassium ... Intracellular Shift ... #high #nephrology
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Hyperkalemia Differential ... Algorithm R/O Pseudo-hyperkalemia ... TTKG should be high ... Algorithm #causes #potassium ... #high #pathophysiology
Oxygen-Hemoglobin Dissociation Curve Left Shift (↓ O2 unloading to tissue), Left = Lower: • ↓ H+ (↑
Curve Left Shift ... Temperature Right Shift ... ↑ 2,3-BPG • High ... Dissociation #Curve #pathophysiology ... #pulmonary #respiratory
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management ... Dialysis Serum potassium ... blocks, QRS axis shift ... , asystole #hyperkalemia ... #potassium #high
Hyperkalemia Management Algorithm • Treat the cause & optimize hemodynamics and ventilation • Reconsider treatment leadingto
Hyperkalemia Management ... and parenteral potassium ... Intracellular K+ Shift ... Algorithm #treatment #potassium ... #high
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine Urine K+
patients with hypokalemia ... the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... syndrome #hypokalemia ... #urine #potassium
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