47 results
Pivot-Shift Test in ACL-deficient Knee

This patient has pathologic varus alignment across the knee and a chronic
Pivot-Shift Test ... be performing a high-tibial ... dr.dold.md #Pivot #Shift ... #PivotShift #test
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift ... Transcellular shifts ... Diagnosis #Algorithm #nephrology ... #low #potassium
Causes of Hyperkalemia - Differential Diagnosis Algorithm
 • Increased Intake
 • Reduced Excretion (IV potassium with
Excretion (IV potassium ... Transcellular Shift ... #Hyperkalemia #Nephrology
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
minutes) Decrease potassium ... • IV Fluids Shift ... potassium intracellularly ... Sodium bicarbonate Potassium ... #nephrology
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Curve Left Shift ... Temperature Right Shift ... ↑ 2,3-BPG • High ... Dissociation #Curve #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Transcellular Shift ... Algorithm #causes #potassium ... #low #pathophysiology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Decreased renal potassium ... Drugs Increased potassium ... Normal, Renin High ... hypoplasia Aldosterone high ... Diagnosis #algorithm #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... creatinine) • Cell shift ... mmol creatinine) High ... hypokalemia #urine #potassium ... algorithm #diagnosis #nephrology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Increased EC shift ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology ... #Nephrology #Nephron