54 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... • Euvolemic (Low ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... #Algorithm #nephrology
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... and Workup Step ... • nephrotic syndrome ... #Diagnosis #Workup ... #Algorithm #Nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... Cirrhosis, Nephrotic syndrome ... Cerebral salt wasting ... Primary polydipsia, Low ... diagnosis #sodium #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Cerebral salt wasting ... Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... #nephrology
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Hypercalcemia Low ... disease, Milk Alkali Syndrome ... disease, Viral Syndromes ... #nephrology #PTH
Cushing Syndrome Testing Algorithm
INDICATIONS FOR TESTING:
 • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension)
Testing:
Cushing Syndrome ... Suspected Cushing syndrome ... Cortisol, Saliva • Low ... dexamethasone suppression test ... ARUPLabs #Cushing #Syndrome
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 • Tea and Toast Syndrome, Beer Potomania - Low solute
Hyponatremia - Differential ... Tea and Toast Syndrome ... Beer Potomania - Low ... failure, nephrotic syndrome ... Algorithm #causes #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
syndromes ... - Gitelman syndrome ... - Hungry bones syndrome ... Differential #Diagnosis #Low ... Classification #Causes #Workup
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
Ifosfamide - Fanconi syndrome ... Panitumumab- renal wasting ... Trastuzumab • Hyponatremia ... Cisplatin- renal salt wasting ... Ifosfamide - Fanconi syndrome
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Cerebral salt wasting ... syndrome Hypovolemia ... Stress, Drugs, Syndrome ... • Nephrotic syndrome