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diagnosis hematology management sle differential erythematosus systemic treatment algorithm anemia classification druginduced falciparum hemolytic microscopy summary antiphospholipid apls blood cerebritis
P. falciparum ring forms on a thin smear - Dr. Christina Dean @deanchr3 #Plasmodium #falciparum #Rings #Smear #Hematology
@deanchr3 #Plasmodium ... #Rings #Smear #Hematology ... #Microscopy #Clinical ... #Pathology #malaria
Plasmodium Falciparum Blood Smear. Key features suggesting Plasmodium falciparum: - extreme parasitemia - normocytic RBCs (vivax, ovale prefer big
Plasmodium Falciparum ... P. falciparum causes ... ~75% of human malaria ... #peripheral #clinical ... #microbiology #malaria
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Anemia Intrinsic Causes ... Bartonella, Babesia, Malaria ... , spider/snake bites ... Intravascular Causes ... classification #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... & NPSLE rare, Malar ... 40, F:M 9:1 • Clinical ... Manifestations: Malar ... comparison #table #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... • Systemic Lupus ... • Insect Bites ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes ... differential #diagnosis #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Diagnosis of Lupus ... CNS #neurology #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... Photosensitivity • Malar ... Erythematosus #Diagnosis #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Leishmaniosis, malaria ... Drugs, Unknown cause ... treatment #summary #rheumatology
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