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diagnosis differential causes hematology extravascular hemolytic algorithm autoantibodies bleeding classification erythematosus hemostasis mimickers pediatrics peds purpura signs sle symptoms systemic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... usually IgG) (e.g. lupus ... • Infections: Malaria ... #Hemolytic #Intravascular ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
and Intravascular ... PK deficiency Intravascular ... Infections • Malaria ... anemia • ... Algorithm #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Diagnosis for Hemolytic ... Anemia Intrinsic ... Bartonella, Babesia, Malaria ... IVIG infusion Intravascular ... classification #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Arthritis 69% - Malar ... Lymphadenopathies 7% - Hemolytic ... anemia 4% - Myositis ... #differential #rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Purpura or Easy Bruising ... SLE (systemic lupus ... (disseminated intravascular ... - Bernard—Soulier ... Scurvy #Purpura #Bruising
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... inhibitor and lupus ... of factor VII should ... , disseminated intravascular ... #Bleeding #Bruising
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