16 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... B19 infection Malar ... lesions • Discoid lupus ... #skin #rashes #differential ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Arthritis 69% - Malar ... (aPL) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Features That Differentiate ... associated with rheumatologic ... presentation of systemic lupus ... trapezius ridges or shoulders ... it difficult to differentiate
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Rheumatica • Pain ... Diffuse muscle pain ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
of Bone/Joint Pain ... common sites: hip, shoulder ... • Differentiate ... SickleCell #Disease #differential ... diagnosis #causes #hematology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... healthy adults, and should ... , Drug-induced Lupus ... ANA #patterns #rheumatology ... #diagnosis #differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgG) (e.g. lupus ... • Infections: Malaria ... Extravascular #Causes #differential ... #diagnosis #hematology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... Inflammatory joint pain ... and fingers, or pain ... the face (many differential ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... Arthritis: • Joint pain ... Photosensitivity • Malar ... Erythematosus #Diagnosis #Rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Polyarteritis Nodosa (PAN ... (RA), Systemic lupus ... swinndong #Aortitis #Differential ... #Diagnosis #rheumatology