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diagnosis differential erythematosus pain arthritis systemic treatment dermatology disease druginduced msk summary vasculitis workup antinxp2 antinxp2dm approach bone cerebritis classification
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... B19 infection Malar ... lesions • Discoid lupus ... #joint #pain #skin ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Manifestations: Malar ... Positive in 60-80% of cases ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
& NPSLE rare, Malar ... Discontinuation of causal ... Manifestations: Malar ... #table #rheumatology ... #diagnosis #management
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... #Measurement #SLE ... #rheumatology # ... pharmacology #levels #lupus ... #management
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... spondyloarthropathies, lupus ... Like in this case ... Chronic = RA, SLE ... #rheumatology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... ) Inflammatory joint ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... dz difficult to see ... BrighamChiefs #Bone #Joint ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Arthritis: • Joint ... arthropathy • 90% joints ... Photosensitivity • Malar ... Erythematosus #Diagnosis #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
axial (spine, shoulders ... weeks) Can Be Caused ... arthritis • SLE ... Symmetrical: • RA • SLE ... Diagnosis #MSK #rheumatology
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