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diagnosis hematology bleeding differential bruising causes pathophysiology treatment anticoagulation checklist criticalcare hemostasis interpretation platelet table teg thrombocytopenia thromboelastogram thromboelastography warfarin
Hemostasis Physiology The blood's response to blood vessel injury can be viewed as four interrelated steps. Roman
numerals refer to coagulation ... diphosphate; PF-3, platelet ... Pathophysiology #Coagulation ... #Cascade #Hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... cascade is shown ... multicomponent complexes on platelets ... #Coagulation #Cascade ... #platelet #thrombin
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Differential Diagnosis Algorithm ... vs Acquired • Platelet ... Qualitative • Coagulation ... Differential #Diagnosis #Algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Differential Diagnosis Algorithm ... Sequestration Disordered Platelet ... • Vasculitis Coagulation ... deficiencies Coagulation ... Differential #Diagnosis #Algorithm
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... pheresis - Platelets ... proteins, all coagulation ... Volume #Hematology #Management
Management of Supratherapeutic INR and Complications of Anti-Coagulation #Management #Supratherapeutic #INR #Bleeding #Algorithm #Ddxof
Management of Supratherapeutic ... Complications of Anti-Coagulation ... #Management #Supratherapeutic ... INR #Bleeding #Algorithm
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... causes #treatment #management
THROMBOELASTOGRAPHY (TEG) General Principle • A small cuvette is rotated to simulate sluggish venous flow and stimulate clot
problems with coagulation ... cascade and platelet ... Thromboelastography #Diagnosis #Management
Thromboelastography (trademarked as TEG) • Graphical representation of the fibrin polymerization process • Point-of-care anti-coagulation monitoring
Point-of-care anti-coagulation ... routine transfusion algorithms ... amplitude • If ↓ → platelet ... deficiency → give platelets
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Qualitative defect in platelets ... characteristic of a platelet ... inhibitor of a coagulation ... integrity Clotting cascade ... intravascular coagulation
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