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diagnosis hematology causes bruising nephrology disorders glomerular management nephrotic petechiae thrombocytopenia acute aggregometry aki anemia anticoagulation blanching blood bruise coronavirus
Platelet disorders and Aggregometry Glanzmann Thrombasthenia • Defective aggregation to all agonists except ristocetin • Normal platelet,
Platelet disorders ... (either severe Type ... 1 or Type 3) — ... differentiate vWD ... considered first-line testing
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... - Differential ... Diagnosis Algorithm ... vs Acquired • Platelet ... #Diagnosis #Algorithm
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Thrombocytopenia and Platelet ... Diagnosis and Workup ... History: - Prior platelet ... smear, HIV/HCV testing ... Thrombocytopenia #Platelet
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Thrombocytosis - Elevated Platelet ... Count - Differential ... Diagnosis Algorithm ... hematology for workup ... Thrombocytosis #Platelets
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Diagnosis Algorithm ... < 1800/uL, • platelet ... /uL Initial Workup ... #Diagnosis #Algorithm ... #hematology #workup
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... B-symptoms, bruising/bleeding ... anemia, ↑ MCV, ↑/↓ platelets ... #Diagnosis #Algorithm
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Sequestration Disordered Platelet ... #Diagnosis #Algorithm
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
to a low blood platelet ... neutrophils and platelets ... Neutropenia • Platelet ... blood cells or platelets ... blood cells or platelets
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... with or without platelet ... #workup #hematology ... #testing
Bleeding manifestations Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
at > 2 weeks Type ... lowest levels Platelet ... ability to bind platelets ... VWF:RCo/VWF:Ag (differentiate ... VWD type 1 and
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