33 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Acute Respiratory Distress Syndrome – ARDS: Clinical Cheat Sheet

An acute diffuse, inflammatory lung injury, leading to
inflammatory lung injury ... objective assessment“ (e.g ... there is no clear cause ... the underlying cause ... #CriticalCare
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
Medications, Spinal Cord Injury ... ) UOP > 0.5 cc/kg ... Differential #Diagnosis #criticalcare ... #algorithm #treatment ... #management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... Traumatic brain injury ... #Differential #Causes ... Checklist #Diagnosis #Management
Massive Hemoptysis - Diagnosis and Management
 • Definitions: 
   - Hemoptysis = bleeding from
Diagnosis and Management ... respiratory tract (e.g ... has potential to cause ... #treatment #workup ... #pulmonary #criticalcare
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... hemophilia type (e.g ... Chronic Management ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology