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differential joint signs disease sle erythematosus msk rheumatoid syndrome systemic workup approach comparison dermatology druginduced myopathy myositis vasculitis activation ana
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Pain Rash ... lesions • Discoid lupus ... #joint #pain #skin ... #differential #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... • Interstitial lung ... • Shrinking lung ... #pain #differential ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... of hip (rare), Arthritis ... lesions Abdominal pain ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Pain History ... : Is the pain from ... or nerve root Symptoms ... #Pain #MSK #rheumatology ... #differential #diagnosis
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... with temporal arteritis ... Diffuse muscle pain ... #differential #diagnosis ... #comparison #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... shoulders Signs & Symptoms ... pain / swelling ... #diagnosis #management ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Diagnosis Manifestations ... : - Arthritis ... Myositis 4% - Lung ... autoantibodies #signs #symptoms ... #differential #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... • Key point: If ... #Joint #Pain #MSK ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... : • Joint pain ... : • Symptoms limited ... #Rheumatology
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