18 results
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
disorders of Liver & Lung ... Malignancies • Aging ... #RF #rheumatology ... #laboratory #differential ... #diagnosis
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Big picture points ... Often hard to differentiate ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
disease-associated interstitial lung ... LungDisease #CTILD #Diagnosis ... #Differential # ... Comparison #Table ... #Pulmonary #Rheumatology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
RF (rheumatoid factor ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... Rheumatoid #Arthritis #diagnosis ... #management #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Generally affects long ... • Differentiate ... SickleCell #Disease #differential ... #diagnosis #causes ... #hematology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle pain and/or joint ... myopathy) VA Joint ... Myopathies #myopathy #differential ... #diagnosis #comparison ... #rheumatology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
) / Maturation Factor ... approximately how long ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
biliary, renal, lung ... PET-CT Imaging (→ Diagnostic ... antibodies, rheumatoid factor ... #management #phenotypes ... workup #treatment #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... • Shrinking lung ... System Tender points ... #pain #differential ... #diagnosis #rheumatology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
(contains vWF, factor ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology