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differential signs hematology arthritis syndrome joint lupus systemic treatment workup erythematosus leukemia msk rheumatoid adrenal chronic classification comparison dermatology endocrinology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... extramedullary disease ... , fever, joint pain ... ) CLL Symptoms: ... #Oncology #Diagnosis
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... • Interstitial lung ... • Shrinking lung ... #pain #differential ... #diagnosis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Alcohol-induced pain ... : Pain in involved ... Differential Diagnosis ... NonHodgkins #comparison #oncology ... #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Cell Disease Vaso-occlusive ... Generally affects long ... dz difficult to see ... #diagnosis #causes ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... #workup #oncology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Myositis 4% - Lung ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
and Management ... or metastatic disease ... ketoconazole, etomidate) Symptoms ... anorexia, abdominal pain ... pain (10-40%),
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... should be done in ALL ... CMC_IM #Potts #Disease
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Summary Clinical Signs ... demineralization) • Renal disease ... macrocytic • Bone pain ... plasma clonal cell ... #Management #oncology
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