62 results
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Abscess Pathophysiology ... Lung Abscess - Clinical ... : • CBC - Leukocytosis ... #differential #causes
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... disorders • Celiac disease ... effect following treatment ... #Hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long ... #differential #diagnosis ... #causes #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
comorbidities: • CBC ... BNP/NT-proBNP, d-dimer ... ventilated • CXR, Lung ... of AECOPD: • Clinical ... #Exacerbation #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... Treatment: •
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... severity of the disease ... anti-NXP2 Abs Lung ... #rheumatology #dermatology ... #diagnosis
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epidermis from dermis Clinical ... - Erosions and crusts ... not feasible CMC ... #Management #dermatology
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
, causes and management ... cryoglobulinemia vasculitis Clinical ... involvement - Joint ... neuropathy Treatment ... with refractory disease
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Advanced HIV (CD4 ... : Clinical Manifestations ... Lung Disease: ... • Clinical (Symptoms