53 results
diagnosis differential hematology causes algorithm signs symptoms nutrition neurology classification hepatology korsakoff lactate management vitaminb12 acidosis clinical dermatology disorders hemolysis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... lncreased WBCs - Polychromatic ... Hemolysis - Polychromatic ... • Early Iron Deficiency ... #Normocytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... ' nucleotidase deficiency ... lead poisoning • Polychromasia ... decrease - PNH • Polychromasia ... ARUPLabs #Hemolytic #Anemia
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... Myelodysplastic syndrome ... Thalassemia, Iron-deficiency ... cells - G-6-PD deficiency ... Hemolytic uremic syndrome
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... Microcytic" • Iron deficiency ... Megaloblastic: Vitamin B12 deficiency ... , Folate deficiency ... Myelodysplastic syndrome
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Anemia - Differential ... Gastrectomy, WHDA syndrome ... , Copper deficiency ... #Anemia #Differential
Gastrointestinal Causes of Iron Deficiency Anemia • Mass lesions: Carcinoma, Large polyps • Inflammatory: Reflux esophagitis,
Causes of Iron Deficiency ... Anemia • Mass ... rubber bleb nevus syndrome ... Gastrointestinal #Iron #Deficiency ... #Anemia #Causes
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... E - Haemolytic anaemia ... Wernicke-Korsakoff syndrome ... Vitamin B12 - Anaemia ... #Vitamins #Deficiency
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... B12 • Folate deficiency
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Megakaryopoiesis • B12 Deficiency ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... , GATA2 deficiency ... , CTLA4 deficiency ... marrow-failure syndromes
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