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diagnosis hematology management differential causes chronic cll leukemia lymphocytic mds myelodysplastic workup algorithm classification clinical crisis disease features foam foamed
Treatments for Sickle Cell disease #Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Treatments for Sickle ... Cell disease ... #Sicklecell #sicklecelldisease ... sicklecellanemia, #sicklecells ... sickle #hematology #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
• Marrow Aplasia ... lncreased WBCs - Polychromatic ... Hemolysis - Polychromatic ... RBCs - Sickle Cells ... , Target Cells
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... number of CD34+ cells ... anemia Treatment ... #Anemia #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Treatment: • Consider ... stem cell transplant ... Medicine @SCVMCMed #Aplastic ... #management #treatment
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... cytopenias (usually anemia ... Allogeneic stem cell ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... • Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... diagnosis #workup #oncology
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Crisis Sickle-cell ... These cells can ... ischaemia. 2) Aplasia ... of the baseline anaemia ... deficiency #SickleCell
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Manifestations of Sickle Cell ... Acute sickle cell ... Supportive with treatment ... hepatomegaly and anemia ... BrighamChiefs #SickleCell
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... 5) Symptoms of anemia ... Transformation to large cell ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology
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