20 results
Aplastic Anemia Summary

 • Definition
 • Pathophysiology
 • DDx: AA vs Hypocellular MDS
 • Expectation
 •
Aplastic Anemia ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis ... #oncology #hematololgy
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Reticulocytosis/polychromasia ... breakdown • Anaemia ... Hemolysis #Hemolytic #Anemia ... Differential #Causes #Workup
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... • Marrow Aplasia ... lncreased WBCs - Polychromatic ... Hemolysis - Polychromatic ... #Normocytic #Anemia
Causes of Aplastic Anemia

#Aplastic #Anemia #Causes #Pathophysiology #Pathology #Treatment #Management #Differential
Causes of Aplastic ... Anemia #Aplastic ... #Anemia #Causes ... Pathophysiology #Pathology #Treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... mutations) • Immune Aplastic ... anemia Treatment ... #Anemia #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... • Symptomatic anemia ... Treatment: • Consider ... Medicine @SCVMCMed #Aplastic ... #management #treatment
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... lead poisoning • Polychromasia ... decrease - PNH • Polychromasia ... ARUPLabs #Hemolytic #Anemia ... Diagnosis #Algorithm #workup
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... cytopenias (usually anemia ... only curative treatment ... Diagnosis #Management #treatment ... #hematology #oncology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Pancytopenia #Workup
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Pancytopenia #Workup