14 results
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... , spider/snake bites ... HUS, DIC, HELLP, AS ... #Differential #
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Disorders - Blood Gas ... Steps for Blood Gas ... Differentials? ... Renal failure (uremia ... - Rapid saline infusion
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... focus on improving perfusion ... Reduced tissue perfusion ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Classification and Differential ... delivery: Hypoxemia, Anemia ... Nitroprusside infusion ... Classification #Differential ... #TypeA #TypeB #lactate
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
Acidosis with Anion Gap ... paraldehyde L - Lactate ... that results in lactate ... linezolid U - Uremia ... Acidosis #diagnosis #differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Grafts, Valves, AS ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate ... #Hemolysis #Differential
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis - Differential ... Shock, Severe Anemia ... Overgrowth • Presents as ... Difficult to diagnosis as ... Lactic #Acidosis #Differential
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... the serum that has ... disease #LDH #Lactate ... Dehydrogenase #Elevated #differential
LACTATE DEHYDROGENASE.
•	Cytoplasmic enzyme present in tissues throughout the body. 
•	Oxidoreductase, enzyme of the anaerobic metabolic pathway.
•	Heart,
LACTATE DEHYDROGENASE ... production, & lactate ... • LDH serves as ... from transudate effusions ... through LDH-5, have differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... • hemolytic anemia ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... disease #hemolytic #anemia