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diagnosis rheumatology erythematosus systemic anesthesiology checklist intraoperative treatment differential disease druginduced signs summary symptoms activation ana antibodies antinuclear antiphospholipid apls
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... , oral ulcers, Lupus ... • Immunologic Workup ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... block • Sjogren syndrome ... polymyositis overlap syndrome ... #Systemic #Lupus ... #management
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... Demyelinating syndromes ... haemolytic Coombs positive ... #SLE #systemic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Erythematosus #SLE ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
) - Diagnostic Algorithm ... specific, so if positive ... choices AND management ... options (see below ... #Workup #Endocrinology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... erythematosus (SLE ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... ANA #patterns #rheumatology
Can’t Intubate, Can’t Oxygenate (CICO) - Guidelines for Crises in Anaesthesia This is the last resort when
optimal airway management ... Access – FoNA (see ... extension. ❽ Operator position ... Anesthesiology #Anesthesia ... #Workup
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia Hypertension is most commonly due to inappropriate depth of
Airway • Check position ... be diagnostic – see ... overload / TURP syndrome ... Checklist #Diagnosis #Management ... #Workup
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... #Diagnosis #Management ... #Hematology #Rheumatology
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