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diagnosis causes rheumatology management algorithm cardiology signs classification dermatology syndrome lupus oncology sle workup clinical comparison disease erythematosus infectiousdiseases table
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
autoantibodies: positive ... • Blood smear: Differential ... → schizocytes, Positive ... FOR a cause → Systematic ... management #treatment #rheumatology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Features of hematologic ... malignancy: • Symptoms ... : B-symptoms, bruising ... hepatomegaly • Labs: anemia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... ) Blood (75%): Anemia ... haemolytic Coombs positive ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
thickening Signs and Symptoms ... calcinosis • Pulmonary ... disease), PAH (pulmonary ... Scleroderma #SSc #rheumatology ... diagnosis #signs #symptoms
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Autoimmune Diseases: • Systemic ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... Idiopathic JAK-2 Positive ... Cyanosis without Pulmonary ... Chronic Chest Symptoms ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... PD deficiency, Pulmonary ... key #diagnosis #differential ... #hematology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Chronic hemolytic anemia ... heart disease Systolic ... multifactorial mechanisms Hematologic ... disorders, lenectomy Systemic ... Classification #Diagnosis #Differential
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... Iron deficiency anemia ... Grooves • Any systemic ... #Secondary #dermatology ... #Differential #
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Dyspnea - Differential ... - Tamponade Pulmonary ... Transverse myelitis • Hematology ... : - Anemia • ... #dyspnea #sob #differential
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