16 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus #Nephritis #SLE ... #Classification ... differential #diagnosis #management ... #nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... , Seizure disorders ... Erythematosus #SLE ... #CNS #neurology ... cerebritis #diagnosis #management
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... prognosis • Nodular ... - 5% RS cells absent ... Lymphoproliferative #Disorders ... #Classification
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
toxic or metabolic disorder ... grand mal) - Absence ... psychological disorder ... Pseudoseizures #GrandMal #Classification ... #Diagnosis #Neurology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... severity (ISN/RPS classification ... by 12 months Classification ... #rheumatology #nephrology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... least 2 joints • Neurologic ... #EULARACR #Classification ... #Criteria #SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Erythematous, macular ... ) • Endocrine disorders ... dysfunction, and mood disorder
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... skin injury) • Neurologic ... Oral aphthae : SLE ... • Arthritis: SLE ... Syndrome #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
: decreased or absent ... Evaluate for NMO, SLE ... : - SLE - Neurosarcoidosis ... Myelitis #diagnosis #management ... #neurology #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... rheumatoid arthritis, SLE ... Ocular- 50%: Ptosis ... Gravis #diagnosis #management ... #neurology