16 results
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... dosing and bridging ... #Oral #Anticoagulant ... #Loading #DVT #Pharmacology ... #Hematology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
first variceal bleeding ... gastropathy • Dosing ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology ... #indications #dosing
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Vascular System - Congenital ... Coagulation #Bleeding ... Diagnosis #Algorithm #Causes ... #Hematology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... interactions and bleeding ... risk during follow-up ... recurrent VTE and bleeding ... Anticoagulation #Management #Hematology
Recurrent / Breakthrough DVT During Anticoagulation

Subtherapeutic Anticoagulation
Hypercoagulable State 
 - Antithrombin deficiency 
 - Hypercoagulability ot
Breakthrough DVT During ... Structural - Pelvic masses ... syndrome - Congenital ... anticoagulation #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... management #algorithm #pharmacology ... decisionaid #cardiology #hematology ... #warfarin #dosing
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... : Urine Common Uses ... Hemoptysis, GI Bleeding ... #Indications #Pharmacology ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
syndrome • Lupus anticoagulant ... discern these causes ... deficiency • Anticoagulants ... deficiency • Anticoagulant ... Differential #Diagnosis #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Congenital deficiency ... heparin - Other anticoagulants ... Congenital intrinsic ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings: • Bleeding ... Reduction of pro/anticoagulants ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology