23 results
Causes of Jaundice - Prehepatic, Intrahepatic, Extrahepatic

#Diagnosis #Differential #Jaundice #Prehepatic #Intrahepatic #Extrahepatic #Unconjugated #Conjugated

** GrepMed Recommended
- Prehepatic, Intrahepatic ... , Extrahepatic ... Jaundice #Prehepatic #Intrahepatic ... #Extrahepatic # ... Unconjugated #Conjugated
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
drug reactions) Conjugated ... excretion of bilirubin conjugates ... Dysfunction - Biliary ... certain drugs, biliary ... Classification #diagnosis #conjugated
An Approach to Jaundice - Differential Diagnosis

- Increased Production (Prehepatic)
- Decreased Clearance (Intrahepatic + Posthepatic)

Dr. Eric
Decreased Clearance (Intrahepatic ... + Posthepatic) ... Table #Causes #Intrahepatic ... #Preheatic #Posthepatic
Portal Hypertension Differential

#Diagnosis #Hepatology #Differential #PortalHypertension #PortalHTN #Prehepatic #Posthepatic #Intrahepatic
PortalHTN #Prehepatic #Posthepatic ... #Intrahepatic
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Pre-Hepatic - Unconjugated ... II) Hepatic - Conjugated ... on Ultrasound Biliary ... Gallstones • Biliary
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(GGT) - Liver, biliary ... Direct bilirubin (Conjugated ... /DBili) - Biliary ... obstruction, intrahepatic ... Indirect bilirubin (Unconjugated
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Approach to Conjugated ... elevation + >20% conjugated ... No dilation = intrahepatic ... MatthewHoMD #Conjugated
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
hepatitis, Acute biliary ... Cholestatic - Intrahepatic ... Cholestatic - Extrahepatic ... • Biliary: Choledocholithiasis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Biliary: Choledocholithiasis ... , Biliary Stricture ... Choledochal cyst • Intrahepatic ... - Obstruction: Biliary ... injury: ~ 1 Unconjugated
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Cholesterol → ↓ Intrahepatic ... Plasma LDL-C #biliary