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diagnosis management hepatology algorithm aki druginduced cirrhosis differential hepatitis lupus nephrology rheumatology aclf acutekidneyinjury albumin alcoholic chronic classification comparison dil
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... cardiorenal syndrome) • Liver ... tubular necrosis (causes ... prostatic hypertrophy (BPH ... #Kidney #Injury
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Circulation Failure Kidney ... Injury (DILI) ... Failure #Cirrhosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... of Acute Liver ... Liver Injury: ... Liver Injury:
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Skin involvement, Kidney ... non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute ... #Algorithm #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
) - 8g per liter ... ascites removed • Acute ... kidney injury ( ... Management #Cirrhosis #treatment ... #hepatology
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
Guide to Acute Kidney ... Injury (AKI) ... for: - HPI, PMH ... - TTE/liver fxn? ... rhabdo/TLS) Causes
Acute Kidney Injury (AKI) - Management Principles Prerenal - Correct hemodynamic derangements: • If low preload →
Acute Kidney Injury ... Treat underlying liver ... → No specific treatment ... → Stop meds • BPH ... #Kidney #Injury
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... terbinafine, thiazidic, PPI ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
exclude other causes ... : - Acute kidney ... injury with serum ... HCV, DILI, HCC, acute ... Management #Algorithm #hepatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
myalgia, serositis, Kidney ... terbinafine, thiazidic, PPI ... • Immunologic Workup ... Discontinuation of causal ... #diagnosis #treatment
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