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diagnosis dermatology rheumatology differential manifestations oncology classification gangrenosum monoclonal photo signs skin behcet cryofibrinogenemia cryoglobulins dermpath erythematosus gammopathy gpa granulomatosis
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Extravascular lg Deposits: Systemic ... Cold agglutinin disease ... , Pyoderma gangrenosum ... manifestations #dermatology ... #skin #clinical
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
of Cutaneous Vasculitis ... Identification of causes ... Connective tissue disease ... #dermatology #semiology ... lesions #diagnosis #clinical
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
Pyoderma Gangrenosum ... resulting in a vasculitis ... which causes slowly ... a number of systemic ... #Photo #Dermatology
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
appearing during the disease ... , Pyoderma gangrenosum ... leukocytoclastic vasculitis ... differential #diagnosis #dermatology ... #oncology #clinical
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... • Autoimmune diseases ... Henoch-Schönlein purpura) • Cutaneous
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... which may resemble pyoderma ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... Low levels mixed cryoglobulinemia
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... dermatosis • Pyoderma ... gangrenosum • Cutaneous ... (Cryoglobulinemic ... Paraproteinemias #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... ) • Cutaneous Lesions ... like lesions, pyoderma ... (Clinical Dx). ... #diagnosis #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Causes: - Idiopathic ... , breast CA - Hematologic ... DDX: - Pyoderma ... #diagnosis #dermatology
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