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Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... of Systemic Lupus ... Erythematosus (SLE) #Systemic ... Manifestations #Signs ... #Symptoms #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Erythematosus Clinical ... pericarditis • Hematologic ... Criteria #SLE #Systemic
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... joints Nervous system ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Eosinophilia and Systemic ... Signs (DRESS Syndrome ... UCSD Catalog of Clinical ... Images #Clinical ... #Dermatology #SkinRash
Drug Reaction with Eosinophilia and Systemic Signs (DRESS Syndrome): Formerly known as drug hypersensitivity reaction, DRESS
represents
Eosinophilia and Systemic ... Signs (DRESS Syndrome ... UCSD Catalog of Clinical ... Images #Clinical ... #Dermatology #SkinRash
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... heliotrope rash, Shaw sign ... , holster sign, ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
infarction or priapism ... WBC >100k, + lab signs ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
infection with systemic ... or those with systemic ... oral antibiotic treatment ... or those with systemic ... or those with clinical
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... Responsive to Treatment ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
Systemic Therapy ... Carcinoma - AGA Clinical ... First Line Treatment ... Hepatocellular #Carcinoma #Systemic ... #Hepatology #Gastroenterology