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diagnosis anemia extravascular hemolysis hodgkins intravascular lymphoma management warm algorithm antibody classification cold mds myelodysplasia myelodysplastic neutropenia nonhodgkins secondary syndromes
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Hemolytic Anemia ... Spherocytes • Treatment ... • Treatment: Warm ... #hematology #diagnosis ... #comparison
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... • Blood smear: Differential ... 2) LOOK FOR a cause ... diagnosis #management #treatment ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... idiopathic) - Autoimmune ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Cold AIHA • Alloimmune ... Extravascular #Differential ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... iron deficiency, hemolysis ... disorders (e.g. autoimmune ... #hematology #secondary
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... EBV infection, Autoimmune ... #oncology #diagnosis ... #differential # ... hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... - Differential ... hypertension and/or drug treatment ... #Neutropenia #differential ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Out Secondary Causes ... factor (GCSF) treatments ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
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