11 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Summary Mechanisms ... GLP-I receptor agonist ... #Summary #DM2 # ... diabetes #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... GLP-1 receptor agonists ... events TZDs DPP ... comparison #management #endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... GLP-1 Receptor Agonists ... • DPP4i / Gliptins ... #Medications #pharmacology ... pathophysiology #endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Sulfonylurea, TZD, DPP ... GLP-1 receptor agonist ... #Medications #pharmacology ... #comparison #table ... #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
They work primarily ... very similar to DPP4s ... #Pharmacology #Dosing ... #Diabetes #DM2 ... #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Summary Mechanisms ... Ozempic), or daily tablet ... Summary #DM2 #diabetes ... #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... mechanism helps lower primarily ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
Medications - Summary ... Table Aspirin ... Acute stroke • Primary ... #Medications #Summary ... #Table #Pharmacology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
drug to remain stable ... empagliflozin and DPP4 ... #semaglutide #Diabetes ... #Pharmacology # ... Endocrinology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Nephrogenic diabetes ... kidney disease • Primary ... insipidus • Primary ... Diuresis #Nephrology #Pharmacology ... #Medications #Table