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diagnosis management differential hematology lupus erythematosus systemic oncology algorithm dermatology disease neurology signs symptoms table thrombocytopenia antibodies associations autoantibodies cardiology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
La) - Sjogren's syndrome ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Goodpasture's syndrome ... diagnosis #table #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... 50% Cutaneous Vasculitis ... Secondary: CTD: SLE ... Disease • Cogan syndrome ... #dermatology #rheumatology
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... Hypersensitivity vasculitis ... Antiphospholipid-antibody syndrome ... • Vasculitis ... differential #diagnosis #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Associated - SLE ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Takayasu: - Age ... temporal artery - Age ... • Cogan Syndrome ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... diseases: - 10% SLE ... 20% Sjögren's syndrome ... erythematosus (SLE ... classification #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... Polymerase Ill • ANCA Vasculitis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... Algorithm #Causes #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... arteritis, Cogan's Syndrome ... ANCA associated vasculitis ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
to 40 years of age ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
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