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differential causes rheumatology management nephrology vasculitis algorithm classification clinical glomerulonephritis renal rpgn syndromes treatment acidosis actinomyces actinomycosis als aniongap antigbm
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... - Differential Diagnosis ... hemorrhage + rapidly progressive ... Vasculitis - Anti-GBM ... Positive (ANCA + anti-GBM
Systemic Sclerosis Associated Autoantibodies Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis Anti-centromere: Limited skin disease (~93-95%), Pulmonary
Diffuse skin disease ... , Pulmonary fibrosis ... (~93-95%), Pulmonary ... crisis, Rapid progressive ... Autoantibodies #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... With associated pulmonary ... Disease (Goodpasture's ... RPGN #Rapidly #Progressive ... #differential #diagnosis
Jaw Clonus on Physical Exam A 24-year-old man presented with progressive dysphagia, dysarthria, and weakness in his
presented with progressive ... consistent with a diagnosis ... PhysicalExam #Clinical #Video ... #ALS #Neurology ... #NEJM
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 Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
Rapidly Progressive ... of glomerular disease ... + • c-ANCA: anti-proteinase ... #Differential #Diagnosis ... #Nephrology
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
- Differential Diagnosis ... Weakness • Cardio-pulmonary ... disease • Anemia ... Lead toxicity • Progressive ... Peripheral #Weakness #Neurology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... Inflammatory eye disease ... ANCA antibody, Anti-GBM ... Path: rapidly progressive
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... proteinuria, Rapidly progressing ... affects the skin, neurologic ... is 50 years • Progressive ... immune GN (rapidly progressive
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Borrelia (Lyme Disease ... ; Positive for anti-ganglioside ... encephalomyelitis - Progressive ... #Differential #Diagnosis ... #Causes #Neurology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... resulting in rapidly progressive ... hemorrhage Diagnosis ... Goodpastures #AntiGBM #diagnosis ... #nephrology #pulmonary
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