2105 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... blood cells + production ... Unknown cause Treatment ... diagnosis #management #treatment
In ARDS, we know that the lungs are so diffusely injured that the remaining total area
providing lung protective ... #pathophysiology ... #criticalcare #treatment
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
in mesolimbic projection ... in mesocortical projection ... decision-making, language production ... Schizophrenia #pathophysiology
Mechanism of Action of Bile Acid Sequestrants
Bile Acid Sequestrants → ↓ Hepatic Bile Acid Pool →
Expression → ↑ VLDL Production ... Secretion → ↑ LDL Production ... sequestration #pathophysiology
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Initial treatment ... the first-line treatments ... #Pharmacology #Pathophysiology
â–º
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... - inadequate production ... #dka #hhs #pathophysiology
Treatment Schema for Standard-Risk Acute Lymphoblastic Leukemia
Induction: 
 • Vincristine, Steroid (dexamethasone), L-Asparaginase, Intrathecal (IT) methotrexate
Consolidation
Treatment Schema ... Consolidation & CNS protection ... given throughout treatment ... Lymphoblastic #Leukemia #Treatment
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
diagnosis #comparison #treatment ... Endocrinology #Adrenal #pathophysiology
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity Treatment ... Toxicity #Toxicology #Pathophysiology ... #Management #Treatment
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Increased Cell Production ... potassium #low #pathophysiology