78 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... Proteinuria often ... but in severe cases ... Massive proteinuria ... #Classification
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria and/or proteinuria ... hematuria (RBC casts ... #Nephritic #Nephrotic ... Syndrome #Comparison #Algorithm
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... treat non-renal SLE ... therapy to treat class ... treat extra-renal SLE ... #Algorithm #Treatment
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... • Glomerular: Nephrotic ... , Nephritic • ... #KidneyInjury #Causes ... Differential #Diagnosis #Algorithm
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... (MPA) • SLE ... Differential #Diagnosis #Algorithm ... #Causes
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
Lupus Nephritis ... Primer Class I - ... DrFlashHeart #Lupus #Nephritis ... #SLE #Classification ... #Classes #differential
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... new: • Proteinuria ... > 500 mg/d • Nephritic ... with evidence of proteinuria ... #diagnosis #algorithm
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... Hallmark = proteinuria ... severity (ISN/RPS classification ... therapy Goal: proteinuria ... by 12 months Classification
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... Acute Interstitial Nephritis ... ; oliguria • Classic ... , mild tubular proteinuria ... #AIN #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... and >3.5g/day (nephrotic ... range) proteinuria ... #Causes