43 results
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Antidotes: • Apixaban ... Humanized Fab fragment Prothrombin
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
aPTT Prolonged Prothrombin ... - Rivaroxaban, apixaban
Oral anticoagulants and reversal/hemostatic strategies. 

In the elegant tug-of-war between thrombosis and hemostasis, prescribing an anticoagulant
again expected; Prothrombin ... FXaInhibitors #Apixaban
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time ... Time (PTT) Prothrombin ... thematttsai #PT #PTT #Prothrombin
Apixaban Dose Adjustments in Atrial Fibrillation - ABCDs

Age > 80 years 
Body Weight <60kg 
Creatinine >=
Apixaban Dose Adjustments ... 2.5 mg bid #Apixaban
Liver Function Tests (LFTs)
 - Aspartate aminotransferase (AST) 
 - Alanine aminotransferase (ALT) 
 - Alkaline
(Direct) - Prothrombin
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
rivaroxaban #Xarelto #apixaban
Choice of anticoagulant for treatment of pulmonary embolism
 • Malignancy - LMWH
 • To avoid parenteral
- Rivaroxaban; apixaban ... Gl bleed - VKA, apixaban
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Anticoagulation #Dabigatran #Apixaban
Xa Inhibitors - Apixaban and Rivaroxaban 
Oral Xa inhibitors are recommended by CHEST as first-line for
Xa Inhibitors - Apixaban ... dosing schemes for apixaban ... #XaInhibitors #Apixaban