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Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... aPTT Prolonged Prothrombin ... Pre-analytical cause ... intravascular coagulation ... aPTT #Prolonged #Causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Leiden mutation - Prothrombin ... considered in all cases ... intravascular coagulation ... and other causes
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... intravascular coagulation ... discern these causes ... Deficiency of prothrombin ... Acquired inhibitor of prothrombin
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... • Vasculitis Coagulation ... deficiencies Coagulation ... Intravascular Coagulation ... Diagnosis #Algorithm #Causes
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Prothrombin Time ... Time (PTT) Prothrombin ... thematttsai #PT #PTT #Prothrombin
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... Treat primary cause ... • Correct coagulation ... #diagnosis #causes
Simplified Coagulation Cascade and Differential Diagnosis #Coagulation #Cascade #Differential #Diagnosis #Intrinsic #Extrinsic #Pathway #Hematology
Simplified Coagulation ... Diagnosis #Coagulation
Coagulation and kinin pathways #Pharmacology #Pathophysiology #Coagulation #Kinin #Pathways #Cascade #Anticoagulants #Antithrombotics #Thrombolytics
Coagulation and ... Pathophysiology #Coagulation
Coagulation Protein Tests (PT and PTT) #Coagulation #Tests #PTT #algorithm #differential #pathophysiology
Coagulation Protein ... PT and PTT) #Coagulation
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