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clinical ultrasound echocardiogram cardiology diagnosis differential a4c abdominal pulmonary hematology lung effusion plax psax msk aortic gallbladder hemorrhage liver algorithm
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... aPTT Prolonged Prothrombin ... Pre-analytical cause ... intravascular coagulation ... aPTT #Prolonged #Causes
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... • Vasculitis Coagulation ... deficiencies Coagulation ... Intravascular Coagulation ... Diagnosis #Algorithm #Causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Leiden mutation - Prothrombin ... considered in all cases ... intravascular coagulation ... and other causes
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... is simultaneous coagulation ... Treat primary cause ... • Correct coagulation ... #diagnosis #causes
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
levels, D-dimer, prothrombin ... Intravascular #Coagulation
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... disorders CAUSES ... • Secondary Causes ... Kasabach-Merritt syndrome Coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... intravascular coagulation ... discern these causes ... Deficiency of prothrombin ... Acquired inhibitor of prothrombin
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework STRUCTURAL: - PFO: paradoxical emboli - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... intravascular coagulation
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... intravascular coagulation ... (DIC) • Anti-coagulation ... Diagnosis #Algorithm #Causes
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