10 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... Diagnosis: >3 symptoms ... #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG ... diagnosis #management #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... EMG: LMN Signs in ... diagnosis column Treatment
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... skin that are caused ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology ... #oncology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... through Ann Arbor criteria ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Most cases are related ... When present, symptoms ... • "Vasomotor" symptoms ... transformation into MDS or AML ... the reduction of symptoms
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... Diagnosis (Clinical Criteria ... Exclude other AKI causes ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... Common Signs and Symptoms ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
drugs of abuse (e.g ... Serotonin Toxicity Criteria ... Serotonin #Syndrome #Pathophysiology ... #Psychiatry #Diagnosis ... #Signs #Symptoms