42 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Algorithm Symptoms ... of autoimmune disease ... Diagnose PBC if 2/3 criteria
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Etiologies of Cirrhosis ... congenital - Primary biliary ... cirrhosis - α1 ... - Wilson disease ... (Budd-Chiari syndrome
Functional Dyspepsia Syndromes - Epigastric Pain Syndrome (EPS) and Postprandial Distress Syndrome (PDS)
Epigastric Pain Syndrome (EPS):
≥
(PDS) Epigastric ... pathology • Criteria ... >3 months • Symptoms ... pathology • Criteria ... >3 months • Symptoms
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Chronic liver disease ... (cirrhosis or chronic ... failure - 3-5% Cirrhosis ... Fitz-Hugh-Curtis syndrome ... Failure, Pancreatic, Biliary
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... processes like primary biliary ... cirrhosis (PBC) ... with systemic diseases ... (SLE) Signs / Symptoms
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-gp210 - Primary biliary ... cirrhosis (PBC) ... Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
and hepatorenal syndrome ... • Budd Chiari syndrome ... • Infiltrative diseases ... pregnancy • Primary biliary ... Veno-occlusive disease
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Cirrhosis (PBC) ... cholestasis → Cirrhosis ... PBC Signs and Symptoms ... #Cirrhosis #PBC
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... ) - Diagnostic Criteria ... cause of kidney disease ... cause of kidney disease ... #Hepatorenal #Syndrome