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diagnosis management hlh lymphohistiocytosis rheumatology syndrome classification comparison gammopathy hemeonc hepatology hepatorenal hodgkins hrs lymphoma macrophage mas mgrs monoclonal myelitis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... A subset of hemophagocytic ... Histopathologic criteria ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... →Activation of CD8 ... IFN-y) → Excessive activation ... accumulation of clinical ... Assessment • Clinical
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... : Overwhelming clinical ... excessive macrophage activation ... • Bicytopenia Treatment ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Risk factors: Critical ... sequestration and activation ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Hemophagocytic Lymphohistiocytosis ... Clinical Presentation ... Diagnostic Criteria ... #HLH #Hemophagocytic ... Diagnosis #Management #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Immunohistochemical studies (to differentiate ... through Ann Arbor criteria ... Hodgkin Lymphoma Treatment ... classification #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Excessive activation ... Transverse Myelitis - Clinical ... Diagnostic Criteria ... Transverse Myelitis Treatment ... management #neurology #differential
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
sympathetic + ADH activation ... Diagnosis (Clinical ... Criteria): • ↑ ... Treatment Overview ... Hepatorenal #Syndrome #Hepatology
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
does not meet criteria ... for hematologic ... Clinical Clues: ... Complement pathway activation ... microangiopathy Treatment
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