18 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... ) - Differential ... 1000): • DILI (Drug-induced ... liver injury) ... Diagnosis #hepatology
Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... of Acute Liver Injury ... #Diagnosis #Hepatology ... #Causes #Differential ... #Incidence #Table
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis ... #differential # ... hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... obstruction - Drug-Induced ... liver injury ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
- Differential ... Differential Diagnosis ... valproate, azoles), Drugs ... Diagnosis #hepatology ... Transaminitis #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Differential #
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis Table ... Complement-mediated TMA - Drug-induced ... Microangiopathy #TMA #hematology ... #differential # ... diagnosis #HUS
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... 15X ULN - Drugs ... Burak @kwburak #LFTs ... #hepatology #LiverFunctionTests