14 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... (SLE) General: ... Butterfly rash, Vasculitis ... Endocarditis, Aortic ... ) Blood (75%): Anemia
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Malar rash • SLE ... Hypersensitivity vasculitis ... Discoid skin lesions ... • Discoid lupus ... #skin #rashes #differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic Anemia ... Autoimmune • ITP • SLE ... HUS • DIC • Vasculitis ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... - Hemolytic anemia ... Associated - SLE ... #Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemic skin lesions ... such as systemic lupus ... diminished, or tender pulses ... , and SLE) • Urinalysis ... #rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... papulosquamous lesions ... permanent alopecia Differential ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... genotypes): SS, SC, SE ... cardiac valve, vasculitis ... Algorithm #workup #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... < 30 years • Aorta ... claudication, pulse ... Arteritis): • Aorta
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Arterial Thrombosis - Differential ... atherosclerotic lesions ... 19 - PNH - Vasculitis ... pathophysiology #hematology ... #differential #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Lyme disease, Vasculitis ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #joint #pain #differential ... #diagnosis #rheumatology