26 results
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Prolonged PT (INR ... Prolonged PT (INR ... #Differential # ... Algorithm #Causes #Hematology ... #coagulation #disorders
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated aPTT ... / PT - Differential ... #Elevated #aPTT ... #PT #INR #Algorithm ... #Hematology #differential
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... • Steroids • Vasculitis ... Coagulation Proteins ... Bleeding #Bruising #Differential ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... • Disruptions in ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Microangiopathy (TMA) - Differential ... Diagnosis Table ... Metabolism-mediated TMA - Coagulation-mediated ... Microangiopathy #TMA #hematology ... #differential #
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... • Elevation in ... aggregation PT, aPTT ... monitor using INR ... Scoring #diagnosis #hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Abnormal PT and/or aPTT ... Congenital intrinsic coagulation ... intravascular coagulation ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Prolonged PT and aPTT ... the PT and the aPTT ... Causes #diagnosis #differential ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT/PTT ... Fibrinogen: ↓ • PT/INR ... - Hg > 7 - INR ... < 2.3 - APTT ... treatment #management #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Managing warfarin INR ... results of the INR ... hemorrhage, while under-coagulation ... #medications #table ... decisionaid #cardiology #hematology